OVERCOMING POOR SOLUBILITY OF DIMENHYDRINATE: DEVELOPMENT, OPTIMIZATION AND EVALUATION OF FAST DISSOLVING ORAL FILM

Overcoming Poor Solubility of Dimenhydrinate: Development, Optimization and Evaluation of Fast Dissolving Oral Film

Purpose: To develop fast dissolving oral film to address vomiting and nausea in pediatric population.Methods: Oral films of Dimenhydrinate were prepared by solvent water coloring casting method by using hydroxypropylmethyl cellulose E5 (HPMC E5), polyethylene glycol 400 (PEG 400) and croscarmellose sodium.Solubility of dimenhydrinate was enhanced b

read more

Comparison of Different Invasive and Non-Invasive Methods to Characterize Intestinal Microbiota throughout a Production Cycle of Broiler Chickens

In the short life of broiler chickens, their intestinal microbiota undergoes many changes.To study underlying biological mechanisms and factors that influence the intestinal microbiota development, longitudinal data Skin Serum from flocks and individual birds is needed.However, post-mortem collection of samples hampers longitudinal data collection.

read more


Clinical neurorestorative progress in stroke

Liyan Qiao,1,* Jun Lu,2,* Hongyun Huang3–5 1Department of Neurology, Tsinghua University Yuquan Hospital, 2Department of Emergency, 2nd Artillery Hospital, 3Center of Neurorestoratology, Beijing Rehabilitation Hospital, Capital Medical University, 4Beijing Hongtianji Neuroscience Academy, Beijing, 5Neuroscience Institute of Taishan Medical Un

read more